Arturo O. Lluisma, Ph.D.
Research Associate Professor 


Education:
Ph.D. Biology 
Dalhousie University, Canada 

Research Interests: 
Marine genomics, molecular genetics, and bioinformatics; phylogenetics and genetic diversity; algal and microbial biotechnology

Selected Publications:
  • Mendoza CB, Masacupan DJM, Batoctoy DCR, Yu ET, Lluisma AO, Salvador‐Reyes LA. (2019). Conomarphins cause paralysis in mollusk: Critical and tunable structural elements for bioactivity. J Pept Sci., 25(7):e3179.
  • Orosco FL, Lluisma AO (2018) Genetic diversity of Penaeus monodon (Fabricius, 1798) in the Philippines as revealed by mitochondrial Cytochrome Oxidase I (COI). Philipp Agric Sci 101(1):84–92.
  • Boncan DAT, David AM, Lluisma A  (2018) A CAZyme-rich genome of a taxonomically novel rhodophyte-associated carrageenolytic marine bacterium. Mar. Biotechnol.  1–21. DOI: 10.1007/s10126-018-9840-6.
  • Orosco FL, & Lluisma AO (2017) Variation in virome diversity in wild populations of Penaeus monodon (Fabricius 1798) with emphasis on pathogenic viruses. VirusDis. 28(3):262-271
  • Orosco FL, & Lluisma AO (2017) Prevalence, diversity and co-occurrence of the white spot syndrome virus, monodon baculovirus and Penaeus stylirostris densovirus in wild populations of Penaeus monodon in the Philippines. Dis Aquat Organ 125(3):199–206.
  • Li Q, Barghi N, Lu A, Fedosov AE, Bandyopadhyay PK, Lluisma AO, Concepcion GP, Yandell M, Olivera BM, Safavi-Hemami H (2017) Divergence of the venom exogene repertoire in two sister species of Turriconus. Genome Biol. Evol. 9(9):2211–2225. 
  • Boncan DAT, Uy IDC, Tayco CC, Lluisma AO (2016) Preliminary Discovery of Repetitive Elements in the Genome of the Sea Cucumber Holothuria scabra Jaeger, 1833. Philippine Journal of Science 145(4): 339-355.
  • Barghi N, Concepcion GP, Olivera BM, Lluisma AO (2016) Characterization of the complete mitochondrial genome of Conus tribblei Walls, 1977. Mitochondrial DNA 27(6): 4451-4452.
  • Dumilag RV, Orosco FL, Lluisma AO (2016) Genetic diversity of Kappaphycus species (Gigartinales, Rhodophyta) in the Philippines. Systematics and Biodiversity 14:5, 441-451. DOI: 10.1080/14772000.2016.1157643.
  • Barghi N, Concepcion GP, Olivera BM, Lluisma AO (2016) Structural features of conopeptide genes inferred from partial sequences of the Conus tribblei genome. Molecular Genetics and Genomics 291(1): 411-422. DOI 10.1007/s00438-015-1119-2 
  • Onda DFL, Azanza RV, Lluisma AO (2015) Potential DMSP-degrading Roseobacter clade dominate endosymbiotic microflora of Pyrodinium bahamense var. compressum (Dinophyceae) in vitro. Archives of Microbiology. 197(7): 965-971. DOI: 10.1007/s00203-015-1133-0 
  • Barghi N, Concepcion GP, Olivera BM, Lluisma AO (2015) Comparison of the venom peptides and their expression in closely related Conus species: insights into adaptive post-speciation evolution of Conus exogenomes. Genome Biology and Evolution 7 (6): 1797-1814. DOI:10.1093/gbe/evv109 
  • Marquez GPB, Reichardt WT, Azanza RV, Onda DFL, Lluisma AO, Montaño MNE (2015) Dominance of Hydrogenotrophic Methanogens at the Peak of Biogas Production in Thalassic Digesters. Waste and Biomass Valorization 6: 201-207 DOI: 10.1007/s12649-014-9325-4 
  • Barghi N, Concepcion GP, Olivera BM, Lluisma AO (2015) High conopeptide diversity in Conus tribblei revealed through analysis of venom duct transcriptome using two high-throughput sequencing platforms. Marine Biotechnology 17 (1): 81-98 DOI: 10.1007/s10126-014-9595-7 
  • Tablizo FA, Lluisma AO (2014) The mitochondrial genome of the red alga Kappaphycus striatus ("Green Sacol" variety): complete nucleotide sequence, genome structure and organization, and comparative analysis. Marine Genomics 18: 155–161 DOI: 10.1016/j.margen.2014.05.006.
  • Chato-Salvador, RC, Tablizo FA, Lluisma AO (2014) Non-enzymatic isolation of somatic cells from Kappaphycus spp. and Eucheuma denticulatum (Solieriaceae, Rhodophyta). European Journal of Phycology 49(4): 486-492 DOI: 10.1080/09670262.2014.977963
  • Onda D, Lluisma AO, Azanza RV (2014) Development, morphological characteristics and viability of temporary cysts of Pyrodinium bahamense var. compressum (Dinophyceae) in vitro. European Journal of Phycology 49: 265-275. [DOI:10.1080/09670262.2014.915062] 
  • Dumilag RV, Lluisma AO (2014) Resolving the phylogenetic affinities of Kappaphycus inermis within the genus Kappaphycus (Gigartinales, Solieriaceae) using mitochondrial and plastid markers. Phytotaxa 162(4): 223-231. [http://dx.doi.org/10.11646/phytotaxa.162.4.5] 
  • Dumilag RV, Liao LM, Lluisma AO (2014) Phylogeny of Betaphycus (Gigartinales, Rhodophyta) as inferred from COI sequences and morphological observations on B. philippinensis. Journal of Applied Phycology, 26(1): 587-595. [http://dx.doi.org/10.1007/s10811-013-0063-y] 
  • Reichardt WT, Reyes JM, Pueblos MJ, Lluisma AO (2013) Impact of milkfish farming in the tropics on potentially pathogenic vibrios. Marine Pollution Bulletin 77:325-332. [http://dx.doi.org/10.1016/j.marpolbul.2013.09.018] 
  • Tayco CC, Tablizo FA, Regalia RS, Lluisma AO (2013) Characterization of a κ-Carrageenaseproducing marine bacterium, Isolate ALAB-001. Philippine Journal of Science 142: 45-54. 
  • Onda DFL, Benico G, Sulit AF, Gaite PL, Azanza RV, and Lluisma AO (2013) Morphological and molecular characterization of some HAB-forming dinoflagellates from Philippine waters. Philippine Science Letters 6(1): 97-106. [http://www.philsciletters.org/article.2013n1.11.htm] 
  • Malonzo MH, Ravago-Gotanco RG, Lluisma AO (2013) Effects of migration patterns on estimates of dispersal rates inferred from genotypic data: a simulation based study focused on the software STRUCTURE (Short Communication). Philippine Science Letters 6 (1) . [http://www.philsciletters.org/shortcomm.2013n1.4p5.htm] 
  • Olivera BM, Watkins M, Bandyopadhyay P, Imperial JS, de la Cotera EPH, Aguilar MB, Vera EL, Concepcion GP, and Lluisma A. (2012) Adaptive radiation of venomous marine snail lineages and the accelerated evolution of venom peptide genes. Annals of the New York Academy of Sciences, 1267: 61–70. [http://dx.doi.org/10.1111/j.1749-6632.2012.06603.x]
  • Lluisma AO, Milash BA, Moore B, Olivera BM, Bandyopadhyay PK (2012) Novel venom peptides from the cone snail Conus pulicarius discovered through next-generation sequencing of its venom duct transcriptome. Marine Genomics 5: 43–51. [http://dx.doi.org/10.1016/j.margen.2011.09.002] 
  • Heralde III FM, Kantor YI, Astilla MAQ, Lluisma AO, Geronimo R, Aliño PM, Watkins M, Corneli PS, Olivera BM, Santos AD, Concepcion GP (2010) The Indo-Pacific Gemmula species in the subfamily Turrinae: Aspects of field distribution, molecular phylogeny, radular anatomy and feeding. Philippine Science Letters vol. 3 no. 1 available online at http://www.philsciletters.org/article.20105.htm.
  • Montes HR, Pobre KF, Lluisma AO (2008) Phylogenetic affiliation of the "Endong"/"Spaghetti" variety of E. denticulatum as revealed by molecular data. Phil. Agricultural Scientist 91: 86- 93.
  • Lluisma AO, López-Vera E, Bulaj G, Watkins M, Olivera BM (2008) Characterization of a novel ψ- conotoxin from Conus parius Reeve. Toxicon 51: 174-180.
  • Lluisma AO, Pante MJR, Montaño MNE (2008) Marine Biotechnology. Pages 113-124 in: Peczon BD and Manalo AJ, Straight Talk on Biotechnology, Vol. 1. Ateneo de Manila University Press, Quezon City.
  • Butardo VM, Ganzon-Fortes ET, Silvestre VA, Bacano-Maningas MBI, Montaño MNE, Lluisma AO. 2003. Isolation and classification of culturable bacteria associated with ice-ice disease in Kappaphycus and Eucheuma. The Philippine Scientist 40:223-236 
  • Lluisma AO, Karmacharya N, Zarka A, Ben-Dov E, Zaritsky A, Boussiba S (2001) Suitability of Anabaena PCC7120 expressing mosquitocidal toxin genes from Bacillus thuringiensis subsp. israelensis for biotechnological application. Applied Microbiology and Biotechnology 57: 161- 166. 
  • Trono GC, Lluisma AO, Montaño MNE (2000) Primer on Farming and Strain Selection of Kappaphycus and Eucheuma in the Philippines. Published by PCAMRD, UPMSI and UNDP, Quezon City.
  • Lluisma AO, Ragan MA (1999) Characterization of the UDPglucose pyrophosphorylase gene from the marine red alga Gracilaria gracilis. Journal of Applied Phycology 10: 581-588. 
  • Lluisma AO, Ragan MA (1999) Occurrence of closely spaced genes in the nuclear genome of the agarophyte Gracilaria gracilis. Journal of Applied Phycology 11: 99-104.
  • Lluisma AO, Ragan MA (1998) Characterization of a galactosyl-1-phosphate uridylyltransferase gene from the marine red alga Gracilaria gracilis. Current Genetics 34: 112-119.
  • Lluisma AO, Ragan MA (1998) Cloning and characterization of a nuclear gene encoding a starchbranching enzyme from the marine red alga Gracilaria gracilis. Current Genetics 34: 105- 111. 
  • Lluisma AO, Ragan MA (1997) Expressed Sequence Tags (ESTs) from the marine red alga Gracilaria gracilis. Journal of Applied Phycology 9: 287-293. 
  • Lluisma AO, Ragan MA (1995) Relationships among Eucheuma denticulatum, Eucheuma isiforme and Kappaphycus alvarezii (Gigartinales, Rhodophyta) based on nuclear ssu-rRNA gene sequences. Journal of Applied Phycology 7(5): 471-477. 
  • Dawes CJ, Lluisma AO, Trono Jr. GC (1994) Laboratory and field growth studies of commercial strains of Eucheuma denticulatum and Kappaphycus alvarezii. Journal of Applied Phycology. 6:21-24
  • Dawes CJ, Trono Jr.GC, Lluisma AO (1993) Clonal propagation of Eucheuma denticulatum and Kappaphycus alvarezii for Philippine seaweed farms. Hydrobiologia 14: 379-383 
  • Trono Jr. GC, Lluisma AO (1992) Differences in biomass production and carrageenan yields (semirefined and refined) among four strains of farmed carrageenophytes in Northern Bohol, Philippines. Hydrobiologia 247: 223-227 
  • Dawes CJ, Trono Jr. GC, Lluisma AO (1992) Eucheuma and Kappaphycus branch and tissue culture at UPMSI. Proc. 2nd RP-USA Phycology Symposium/Workshop, 6-18 January 1992, Philippines, pp. 163-167
  • Dawes CJ, Trono Jr. GC, Lluisma AO (1992) Culture of Eucheuma denticulatum and Kappaphycus alvarezii. Proc. 2nd RP-USA Phycology Symposium/Workshop, 6-18 January 1992, Philippines, pp. 339-343 
  • Trono Jr. GC, Lluisma AO (1990) Seasonality of standing crop of a Sargassum (Fucales, Phaeophyta) bed in Bolinao, Pangasinan, Philippines. Hydrobiologia 204/205: 331-338.  

Students:

MS Students

Joeriggo Reyes 


Graduated Advisees :

Ph.D. Students

Neda Barghi 

Dissertation Topic: Investigating the evolution, diversification and expression of conotoxins through comparative transcriptomics and genomics of closely related Cocus species (2014)


Humberto Montes, Jr. 

Dissertation Topic:  (2007)


MS Students

David Thomas Gonzales 

Thesis: Whole-genome characterization of a bioactive, sponge-associated marine bacterium using high-throughput sequencing (2017)


Paul Lorenzo Gaite

Thesis: Functional Diversity of carbohydrate-active enzymes (CAzymes) in a metagenome obtained via next generation sequencing of seaweed farm sediments (2014) 


David Thomas Gonzales 

Thesis: A bioinformatics survey on the Metagenome of the red tide dinoflagellate Pyrodinium baghamese var. compressum (2013) 


Richard Dumilag 

Thesis: Phylogeny of Betaphycus (Gigartinales, Rhodophyta) and Related Eucheumatoids as Inferred from COI Sequences (2012) 


David Edric Adao

Thesis: Gut and gill content analysis of the green mussel perna vividis (Linnaeus, 1758) using PCR and microscopy (2012) 


Lilian Pagaduan

Thesis: DNA barcoding or gracilaria and related species in the Philippines (2012)


Deo Florence Onda

Thesis: Bacterial Genetic Diversity, Localization and Association with Pyrodinium bahamese var. compressum (Bohm) Steidinger, Tester & Taylor (2010) 


Alvin Carlos 

Thesis: Genetic diversity of zooxanthellae in marine invertebrates (1999) co-adviser 



Links/Website:

Contact: 
aolluisma@up.edu.ph