Eizadora T. Yu, Ph.D. Professor Associate Dean for Mentoring, Academic Progress and Advancement (ADMAPA), College of Science
Education: Ph.D. Biochemistry and Molecular Biology University of Maryland, Baltimore Country, USA
Research Interests: Microbial
enzymes and biomolecules for biotechnology and health applications Application
of advanced mass spectrometric methods o for
proteomics and metabolomic characterization of biomolecules from target
microorganisms; o for
structural studies of RNA, protein-nucleic acid and protein-protein complexes.
Selected Publications: - Braza MKE, Gazmen JDN, Yu ET and Nellas RB. Ligand-Induced Conformational Dynamics of A Tyramine Receptor from
Sitophilus oryzae. Scientific Reports, 2019, 9, 16725.
- Malto ZBL, Bacal CJO, Diaz MJS, and Yu ET. Local Fungal Endophytes as Rich Sources of Chitinase Genes. Philippine
Journal of Science, 2019, 148(3):575-582.
- Mendoza CB, Masacupan DJM, Batoctoy DCR, Yu ET, Lluisima AO and Salvador-Reyes LA. Conomarphins cause paralysis
in mollusks: Critical and tunable structural elements for bioactivity. Journal of Peptide Science, 2019. e3179.
- Bacal CJO and Yu ET. Cellulolytic Activities of a novel Fomitopsis sp. and Aspergillus tubingensis isolated from Philippine
Mangroves. Phil. Journal of Science 2017, 146(4):403-410.
- Geng H, Sale KL, Tran-Gyamfi M, Lane TW, and Yu ET. Changes in the structure of the microbial community associated
with Nannochloropsis salina following treatments with antibiotics and bioactive compounds. Frontiers in Microbiology,
2016, 7, 1155.
- Geng H, Sale KL, Tran-Gyamfi M, Lane TW, and Yu ET. Longitudinal analysis of microbiota in microalga Nannochloropsis
salina cultures. Microbial Ecology, 2016, 72(1) 14-24.
- Mehnds MT, Yu ET, Strobel GA, Riyaz-Ul-Hassan S, Booth E, Geary B, Sears J, Taatjes CA, Hadi MZ. An Endophytic
Nodulisporium sp. Producing Volatile Organic Compounds Having Bioactivity and Fuel Potential. J Pet Environ Biotechnol.
2012. 3(3).
- Yu ET and Hadi MZ. Bioinformatic processing to identify single nucleotide polymorphism that potentially affect Ape1
function. Mutation Research 2011. 722(2), 140-6.
- Fabris D and Yu ET. Elucidating the higher-order structure of biopolymers by structural probing and mass spectrometry:
MS3D. Journal of Mass Spectrometry 2010. 45(8), 841-60.
- Yu ET, Gaucher SP, Hadi MZ. Probing conformational changes in Ape1 during the progression of base excision repair.
Biochemistry 2010. 49, 3786-96.
- Yu ET, Zendejas FJ, Lane PD, Gaucher SP, Simmons BA, Lane TW. Triacylglycerol accumulation and profiling in the model
diatoms Thalassiosira pseudonana and Phaeodactylum tricornutum (Baccilariophyceae) during starvation. Journal of Applied
Phycology, 2009. 21, 669-681.
- Yu ET, Hawkins A, Eaton J, Fabris D. MS3D structural elucidation of the HIV -1 packaging signal. Proceedings of the
National Academy of Sciences 2008. 105, 12248-12253.
- Yu ET, Hawkins A, Kuntz ID, Rahn LA, Rothfuss A, Sale KL, Young MM, Yang CL, Pancerella CM, Fabris D. The
Collaboratory for MS3D: A New Cyberinfrastructure for the Structural Elucidation of Biological Macromolecules and their
Assemblies Using Mass Spectrometry-based Approaches. Journal of Proteome Research 2008. 7, 4848-4857.
- Zhang Q, Yu ET, Kellersberger KA, Crossland E, Fabris D. Toward building a database of bifunctional probes for the MS3D
investigation of nucleic acids structures. Journal of the American Society for Mass Spectrometry 2006. 17, 1570-81.
- Akinsiku O, Yu ET, Fabris D. Mass spectrometric investigation of protein alkylation by the RNA
footprinting probe kethoxal. Journal of Mass Spectrometry 2005. 40, 1372-1381.
7. Yu ET, Zhang Q, and Fabris D. Untying the FIV Frameshifting Pseudoknot Structure by MS3D. Journal of Molecular Biology
2005. 345, 69-80.
- Kellersberger KA, Yu ET, Merenbloom SI, Fabris D. Atmospheric pressure MALDI-FTMS of normal and chemically modified
RNA. Journal of the American Society for Mass Spectrometry 2005.16, 199-207.
- Yu ET and Fabris, D. Toward multiplexing the application of solvent accessibility probes for the investigation of RNA 3D
structures by electrospray ionization-Fourier transform mass spectrometry. Analytical Biochemistry 2004. 334, 356-66.
- Kellersberger KA, Yu ET, Kruppa G, Young M, Fabris D. Top-down characterization of Nucleic Acids Modified by Structural
Probes Using High-Resolution Tandem Mass Spectrometry and Automated Data Interpretation. Analytical Chemistry 2004.
76, 2438-2445.
- Yu ET and Fabris D. Direct probing of RNA structures and RNA-protein interactions in the HIV-1 packaging signal by
chemical modification and electrospray ionization Fourier transform mass spectrometry. Journal of Molecular Biology 2003.
330, 211-23.
- Juinio-Meñez MA, Magsino R, Ravago-Gotanco R, Yu ET. Genetic structure of Linckia laevigata and Tridacna crocea
populations in the Palawan shelf and shoal reefs. Marine Biology 2003. 142, 717-726.
- Yu ET, Juinio-Meñez MA, Monje VD. Sequence Variation in the Ribosomal DNA Internal Transcribed Spacer of Tridacna
crocea. Marine Biotechnology 2000. 2, 511-516.
Students: MS Students Renato
Carpina
Lyle
Ijssel De Guzman
Joyce
Lyn Garcia
Vicenzo
Torreno
Lyssa Lao Erle Peralta
Graduated Advisees (past 10 years): MS Students Christine Jurene Bacal , MS Chemistry 2018 Thesis:Characterization of Glycosyl Hydrolases(GHs) from a
Mangrove-dwelling Fomitopsis sp. Isolate Amado Luis Orden ( Co-adviser), MS Chemistry 2018
Thesis:Understanding Monolayer Formation of POPC and POPG in the
Presence of KS-30: An SFG Study
Corazon Ericka Itang, MS Chemistry 2019
Thesis:Profiling of Conopeptides and its Post-Translational
Modifications from the Venom of Conus eburneus
Dessa Camille Batoctoy, MS Chemistry 2019
Thesis:Mass Spectrometry-Based Characterization of Extracellular Enzymes
from Lasiodiplodia spp.
Links/Website:
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